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Lenacapavir: Revolutionary HIV Prevention Drug Named 2024 Breakthrough of the Year
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Lenacapavir: Revolutionary HIV Prevention Drug Named 2024 Breakthrough of the Year

A twice-yearly injection of lenacapavir provided 100% protection against HIV in clinical trials, marking a potential turning point in the fight against AIDS.

December 19, 2024
5 min read
Source: Science Magazine
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Science Magazine named lenacapavir its 2024 Breakthrough of the Year. In clinical trials, the twice-yearly injection provided complete protection against HIV infection — none of the 2,134 women who received the drug in the PURPOSE 1 trial contracted the virus.

The drug works through a novel mechanism, targeting multiple stages of the HIV life cycle simultaneously. Unlike daily pills, the long-acting injection only needs to be administered every six months, dramatically improving adherence.

In clinical trials, the twice-yearly injection provided complete protection against HIV infection — none of the 2,134 women who received the drug in the PURPOSE 1 trial contracted the virus.

"This could be transformative for HIV prevention," said Dr. Anthony Fauci. The breakthrough offers hope that the decades-long AIDS epidemic could finally be brought under control, especially in regions where daily medication regimens are challenging to maintain.

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APA:

Good News Good Vibes. (2024, December 19). Lenacapavir: Revolutionary HIV Prevention Drug Named 2024 Breakthrough of the Year. Retrieved from https://goodnewsgoodvibes.com/en/article/lenacapavir-hiv-prevention-breakthrough-2024

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https://goodnewsgoodvibes.com/en/article/lenacapavir-hiv-prevention-breakthrough-2024

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Last reviewed: March 21, 2026